TY - JOUR
T1 - OCT assessment of morphological changes of the optic nerve head and macula in idiopathic intracranial hypertension
AU - Waisbourd, Michael
AU - Leibovitch, Igal
AU - Goldenberg, Dafna
AU - Kesler, Anat
PY - 2011/12
Y1 - 2011/12
N2 - Objective: To assess the morphologic changes of the optic nerve head and macula in patients with idiopathic intracranial hypertension (IIH) with optical coherence tomography (OCT). Methods: Data was extracted from the medical records and Stratus OCT images of IIH patients. Results: Ninety-one eyes of 48 IIH patients were divided into 3 groups according to their clinical optic disc appearance. Average retinal nerve fiber layer (RNFL) thickness was statistically different between the groups: normal optic disc/mild elevation group (N = 20) - 89 μm (95% CI, 80-98 μm), mild elevation group (N = 51) - 109 μm (95% CI, 101-117 μm), and papilledema group (N = 20) 124 μm (95% CI, 100-153 μm) (P = 0.004). Fast macular thickness map did not demonstrate a significant difference between the groups for most measured macular areas (N = 49 eyes). Conclusions: Peripapillary RNFL measurements correlated with the clinical appearance of the optic discs, suggesting that OCT may assist in the follow up of IIH patients.
AB - Objective: To assess the morphologic changes of the optic nerve head and macula in patients with idiopathic intracranial hypertension (IIH) with optical coherence tomography (OCT). Methods: Data was extracted from the medical records and Stratus OCT images of IIH patients. Results: Ninety-one eyes of 48 IIH patients were divided into 3 groups according to their clinical optic disc appearance. Average retinal nerve fiber layer (RNFL) thickness was statistically different between the groups: normal optic disc/mild elevation group (N = 20) - 89 μm (95% CI, 80-98 μm), mild elevation group (N = 51) - 109 μm (95% CI, 101-117 μm), and papilledema group (N = 20) 124 μm (95% CI, 100-153 μm) (P = 0.004). Fast macular thickness map did not demonstrate a significant difference between the groups for most measured macular areas (N = 49 eyes). Conclusions: Peripapillary RNFL measurements correlated with the clinical appearance of the optic discs, suggesting that OCT may assist in the follow up of IIH patients.
KW - Increased intracranial hypertension
KW - Optical coherence tomography
KW - Papilledema
KW - Pseudotumor cerebri
KW - Retinal nerve fiber layer
KW - Swollen disc
UR - http://www.scopus.com/inward/record.url?scp=81155152732&partnerID=8YFLogxK
U2 - 10.1016/j.clineuro.2011.05.015
DO - 10.1016/j.clineuro.2011.05.015
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C2 - 21700384
AN - SCOPUS:81155152732
SN - 0303-8467
VL - 113
SP - 839
EP - 843
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
IS - 10
ER -