Observations on the innervation of human extraocular muscles

Menachem Sadeh; Lawrence Z. Stern

doi:10.1016/0022-510X(84)90018-2

Observations on the innervation of human extraocular muscles

Research output: Contribution to journal › Article › peer-review

Abstract

The innervation of human extraocular muscles (EOM) was studied using a comprehensive histological and histochemical approach. In contrast to previous concepts, we have demonstrated that the coarse felderstruktur muscle fibers are singly innervated by en plaque endings and that the fine and granular fibrillenstruktur fibers are multiply innervated by en grappe endings. Each of the fine and granular fibers is innervated by a single thin axon that travels along the fiber and sends collaterals to the en grappe endings. These findings may provide a new basis for the correlation of morphological and physiological properties of EOM.

Original language	English
Pages (from-to)	295-305
Number of pages	11
Journal	Journal of the Neurological Sciences
Volume	66
Issue number	2-3
DOIs	https://doi.org/10.1016/0022-510X(84)90018-2
State	Published - 1984
Externally published	Yes

Keywords

Extraocular muscles
Innervation
Neuromuscular junctions

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10.1016/0022-510X(84)90018-2

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title = "Observations on the innervation of human extraocular muscles",

abstract = "The innervation of human extraocular muscles (EOM) was studied using a comprehensive histological and histochemical approach. In contrast to previous concepts, we have demonstrated that the coarse felderstruktur muscle fibers are singly innervated by en plaque endings and that the fine and granular fibrillenstruktur fibers are multiply innervated by en grappe endings. Each of the fine and granular fibers is innervated by a single thin axon that travels along the fiber and sends collaterals to the en grappe endings. These findings may provide a new basis for the correlation of morphological and physiological properties of EOM.",

keywords = "Extraocular muscles, Innervation, Neuromuscular junctions",

author = "Menachem Sadeh and Stern, {Lawrence Z.}",

note = "Funding Information: This study was supported in part by a grant from the Muscular Dystrophy Association. Address for correspondence: Lawrence Z. Stern, M.D., Department of Internal Medicine, Arizona Health Sciences Center, Tucson, AZ 85724, Tel. (602) 626--6609.",

year = "1984",

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PY - 1984

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KW - Neuromuscular junctions

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Observations on the innervation of human extraocular muscles

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