Observations on the innervation of human extraocular muscles

Menachem Sadeh, Lawrence Z. Stern*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The innervation of human extraocular muscles (EOM) was studied using a comprehensive histological and histochemical approach. In contrast to previous concepts, we have demonstrated that the coarse felderstruktur muscle fibers are singly innervated by en plaque endings and that the fine and granular fibrillenstruktur fibers are multiply innervated by en grappe endings. Each of the fine and granular fibers is innervated by a single thin axon that travels along the fiber and sends collaterals to the en grappe endings. These findings may provide a new basis for the correlation of morphological and physiological properties of EOM.

Original languageEnglish
Pages (from-to)295-305
Number of pages11
JournalJournal of the Neurological Sciences
Issue number2-3
StatePublished - 1984
Externally publishedYes


FundersFunder number
Muscular Dystrophy Association


    • Extraocular muscles
    • Innervation
    • Neuromuscular junctions


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