Observations on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological findings

A. Friedmann, F. P. Strietzel, B. Maretzki, S. Pitaru, J. P. Bernimoulin

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Background: Space-maintaining capacity, cell disclusive potential, and stability over time are crucial factors to achieving sufficient bone augmentation with membrane barriers. The case series presented here assessed a new collagen barrier used in bone augmentation. Clinically, the healing pattern, especially in cases of secondary healing, was studied. Methods: Soft tissue healing was documented by photographs, and the size of the dehiscences calculated by image analysis. The measurements were performed on digitized photographs. During reentry, barrier remnants were dissected and histologically evaluated. Results: The mean value for dehiscences was 35.5 mm2; all dehiscences healed within 4 weeks after the exposure became evident. The difference was statistically significant between the week 2 and week 6 visits (P = 0.008) for each previously exposed site. The histologic observation of barrier remnants revealed direct apposition of fibrous and bone tissues on the membrane surface. Conclusion: In cases of membrane exposure, gingival dehiscences always disappeared in the following weeks without affecting the healing process. Histologic results showed barrier stability over a 6-month period, promoting bone regeneration.

Original languageEnglish
Pages (from-to)1616-1623
Number of pages8
JournalJournal of Periodontology
Volume72
Issue number11
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Barrier
  • Collagen
  • Guided bone regeneration
  • Membranes
  • Space maintenance

Fingerprint

Dive into the research topics of 'Observations on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological findings'. Together they form a unique fingerprint.

Cite this