Numerical model of the aortic root and valve: Optimization of graft size and sinotubular junction to annulus ratio

Gil Marom, Rotem Halevi, Rami Haj-Ali, Moshe Rosenfeld, Hans Joachim Schäfers, Ehud Raanani*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Objective: The aim of this study was to determine the influence of aortic annulus (AA) diameter and the ratio of the sinotubular junction (STJ) diameter to the AA diameter on aortic valve hemodynamics and tissue mechanics and to suggest optimal values. Methods: Sixteen cases of aortic roots with AA diameters between 22 and 28 mm and an STJ/AA diameter ratio between 0.8 and 1.4 were numerically modeled. Average coaptation height and mechanical stresses were calculated from 3-dimensional finite element analysis of the aortic valve and root. Five additional fluid structure interaction (FSI) models with an AA diameter of 24 mm and an STJ/AA ratio between 0.6 and 1.4 were also constructed. The material properties of the tissues were from porcine valves and boundary conditions were physiologic and normal blood pressures. Results: In most cases, average coaptation height decreased with an increase in the STJ/AA ratio. Those cases with AA diameters between 24 and 26 mm and an STJ/AA ratio between 0.8 and 1.0 had a relatively large average coaptation height (>3 mm) and similar stress distribution during diastole. The flow shear stress values on the cusps at peak systole increased at the same time as the STJ/AA ratio decreased, similar to the opening area. Conclusions: Relatively large coaptation, low stress in the tissues during diastole, and low flow shear stress during systole is the best combination for cases of AA diameter between 24 and 26 mm with identical STJ diameter. Valve-sparing procedures that prevent AA expansion are preferable.

Original languageEnglish
Pages (from-to)1227-1231
Number of pages5
JournalJournal of Thoracic and Cardiovascular Surgery
Volume146
Issue number5
DOIs
StatePublished - Nov 2013

Funding

FundersFunder number
Tel Aviv University
Nicholas and Elizabeth Slezak Super Center for Cardiac Research and Biomedical Engineering

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