Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue

Dina Carasso, Uzi Eliav, Gil Navon*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A new NMR parameter is suggested as a sensitive tool for monitoring thermal coagulation of liver tissue. That parameter is the proton magnetization exchange time (τMEX) between water and the proteins. τMEX was very sensitive to coagulation and insensitive to temperature, therefore representing only damage to the tissue, independent of effects caused by temperature fluctuations. The measurement of τMEX by two different methods revealed the existence of two or more groups of proteins, characterized by their different transverse relaxation time, and τMEX.

Original languageEnglish
Pages (from-to)1082-1086
Number of pages5
JournalMagnetic Resonance in Medicine
Volume54
Issue number5
DOIs
StatePublished - Nov 2005

Keywords

  • Coagulation
  • Liver
  • NMR
  • Protein-water magnetization exchange
  • Thermal therapy

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