Nuclear Export Inhibition for Radiosensitization: A Proof-of-Concept Phase 1 Clinical Trial of Selinexor (KPT-330) Combined With Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

Yaacov R. Lawrence*, Einat Shacham-Shmueli, Nirit Yarom, Marat Khaikin, Moris Venturero, Sara Apter, Yael Inbar, Zvi Symon, Dan Aderka, Naama Halpern, Raanan Berger, Ben Boursi, Galia Jacobson, Stephen Raskin, Aliza Ackerstein, Ofer Margalit, Sarit Appel, Michael Schvimer, Marsha Crochiere, Fan YangYosef Landesman, Tami Rashal, Sharon Shacham, Talia Golan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)250-255
Number of pages6
JournalInternational Journal of Radiation Oncology Biology Physics
Issue number2
StatePublished - 1 Oct 2022


FundersFunder number
Checkmate Pharmaceuticals
Bristol-Myers Squibb
EMD Serono
Karyopharm Therapeutics

    Cite this