Novel variants in genes related to vesicle-mediated-transport modify Parkinson's disease risk

Keyphrases

• Allele Frequency 20%
• AP1G2 40%
• Ashkenazi Jews 60%
• Autophagy 20%
• Deleterious Variants 20%
• Disease Allele 20%
• Disease Prevention 20%
• Disease Progression 20%
• Frequency Ratio 20%
• Genetic Background 20%
• GnomAD 20%
• Jewish Population 20%
• Leucine-rich Repeat Kinase 2 (LRRK2) 100%
• Mitophagy 20%
• Non-carriers 20%
• Novel Variants 100%
• Odds Ratio 40%
• Oligogenic 20%
• Parkinson Patients 80%
• Parkinson's Disease 80%
• Parkinson's Disease Risk 100%
• PD Analysis 20%
• PIK3C3 60%
• Protein Recycling 20%
• Protein Transport 20%
• Recycling Pathway 20%
• Therapeutic Intervention 20%
• Transport Pathway 20%
• Vacuolar Transporter 20%
• Vesicular Transport 100%
• Vps13 20%
• VPS13D 40%
• VPS35 20%
• Whole-genome Sequence Data 20%

Biochemistry, Genetics and Molecular Biology

• Allele 20%
• Autophagy 20%
• Gene Frequency 20%
• Genetic Background 20%
• LRRK2 100%
• Mediated Transport 100%
• Mitophagy 20%
• Transport Protein 20%
• VPS35 20%
• Whole Genome Sequencing 20%

Neuroscience

• Allele Frequency 7%
• Autophagy 7%
• Mitophagy 7%
• Parkinson's Disease 100%
• Transport Protein 7%
• Whole Genome Sequencing 7%