TY - JOUR
T1 - Novel dioxadiazadecalin podands and their heavy metal ion complexes
AU - Star, Alexander
AU - Goldberg, Israel
AU - Fuchs, Benzion
PY - 2001/2
Y1 - 2001/2
N2 - We present new approaches to podands based on the recently introduced 1,5-dioxa-3,7-diazadecalin (DODAD) core, with functionalized termini in the 2,6- and/or 3,7-positions. Two such podands (12, 14) were prepared and their structures and conformations were studied by NMR. Compound 14 was also analyzed by X-ray and computational (CFF98) techniques. Both podands underwent complexation with cadmium ions, with active participation of the dioxadiazadecalin core cavity. The Cd2+ complexes were studied by NMR and MS techniques. Allosteric effects were observed in the complexation of 12, whereas 14 was preorganized for complexation.
AB - We present new approaches to podands based on the recently introduced 1,5-dioxa-3,7-diazadecalin (DODAD) core, with functionalized termini in the 2,6- and/or 3,7-positions. Two such podands (12, 14) were prepared and their structures and conformations were studied by NMR. Compound 14 was also analyzed by X-ray and computational (CFF98) techniques. Both podands underwent complexation with cadmium ions, with active participation of the dioxadiazadecalin core cavity. The Cd2+ complexes were studied by NMR and MS techniques. Allosteric effects were observed in the complexation of 12, whereas 14 was preorganized for complexation.
KW - Computation
KW - Coordination chemistry
KW - Dioxadiazadecalin
KW - Ion inclusion
KW - Podands
UR - http://www.scopus.com/inward/record.url?scp=0035138666&partnerID=8YFLogxK
U2 - 10.1002/1099-0690(200102)2001:4<729::AID-EJOC729>3.0.CO;2-2
DO - 10.1002/1099-0690(200102)2001:4<729::AID-EJOC729>3.0.CO;2-2
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AN - SCOPUS:0035138666
SN - 1434-193X
SP - 729
EP - 734
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
IS - 4
ER -