We present new approaches to podands based on the recently introduced 1,5-dioxa-3,7-diazadecalin (DODAD) core, with functionalized termini in the 2,6- and/or 3,7-positions. Two such podands (12, 14) were prepared and their structures and conformations were studied by NMR. Compound 14 was also analyzed by X-ray and computational (CFF98) techniques. Both podands underwent complexation with cadmium ions, with active participation of the dioxadiazadecalin core cavity. The Cd2+ complexes were studied by NMR and MS techniques. Allosteric effects were observed in the complexation of 12, whereas 14 was preorganized for complexation.
|Number of pages||6|
|Journal||European Journal of Organic Chemistry|
|State||Published - Feb 2001|
- Coordination chemistry
- Ion inclusion