Novel dioxadiazadecalin podands and their heavy metal ion complexes

Alexander Star, Israel Goldberg, Benzion Fuchs*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We present new approaches to podands based on the recently introduced 1,5-dioxa-3,7-diazadecalin (DODAD) core, with functionalized termini in the 2,6- and/or 3,7-positions. Two such podands (12, 14) were prepared and their structures and conformations were studied by NMR. Compound 14 was also analyzed by X-ray and computational (CFF98) techniques. Both podands underwent complexation with cadmium ions, with active participation of the dioxadiazadecalin core cavity. The Cd2+ complexes were studied by NMR and MS techniques. Allosteric effects were observed in the complexation of 12, whereas 14 was preorganized for complexation.

Original languageEnglish
Pages (from-to)729-734
Number of pages6
JournalEuropean Journal of Organic Chemistry
Issue number4
StatePublished - Feb 2001


  • Computation
  • Coordination chemistry
  • Dioxadiazadecalin
  • Ion inclusion
  • Podands


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