TY - JOUR
T1 - Novel Diagnostic Approach for Acute Pharyngitis
T2 - Combining Machine Learning With Thermal Imaging
AU - Hoffer, Oshrit
AU - Cohen, Moriya
AU - Gerstein, Maya
AU - Shkalim Zemer, Vered
AU - Reichenberg, Yael
AU - Bykhovsky, Dima
AU - Hoshen, Moshe
AU - Cohen, Herman Avner
N1 - Publisher Copyright:
© 2024 Wiley-VCH GmbH.
PY - 2024
Y1 - 2024
N2 - We evaluated the effect of infrared thermography (IRT) on the clinical assessment of bacterial and viral pharyngitis and its impact on the predictive value of the McIsaac score algorithm for streptococcal pharyngitis in children. We also investigated if IRT could distinguish between bacterial and viral pharyngitis. The study included children aged 2–17 years presenting with sore throat and fever over 38°C from November 1, 2021, to April 30, 2022. Of the 76 assessed children, 16 were excluded due to missing data or technical issues, leaving 60 children (32 males, 28 females) divided into three groups: Group A with streptococcal pharyngitis (N = 30), viral pharyngitis (N = 16), and healthy controls (N = 14). McIsaac score and IRT imaging showed a 90% positive predictive value for streptococcal pharyngitis. While IRT alone could not distinguish between bacterial and viral infections, it significantly increased the predictive value when combined with the McIsaac score.
AB - We evaluated the effect of infrared thermography (IRT) on the clinical assessment of bacterial and viral pharyngitis and its impact on the predictive value of the McIsaac score algorithm for streptococcal pharyngitis in children. We also investigated if IRT could distinguish between bacterial and viral pharyngitis. The study included children aged 2–17 years presenting with sore throat and fever over 38°C from November 1, 2021, to April 30, 2022. Of the 76 assessed children, 16 were excluded due to missing data or technical issues, leaving 60 children (32 males, 28 females) divided into three groups: Group A with streptococcal pharyngitis (N = 30), viral pharyngitis (N = 16), and healthy controls (N = 14). McIsaac score and IRT imaging showed a 90% positive predictive value for streptococcal pharyngitis. While IRT alone could not distinguish between bacterial and viral infections, it significantly increased the predictive value when combined with the McIsaac score.
KW - centor score
KW - children
KW - group A streptococcus pharyngitis (GAS-P)
KW - infrared thermography (IRT)
KW - McIssac score
KW - tonsillitis
UR - http://www.scopus.com/inward/record.url?scp=85206155351&partnerID=8YFLogxK
U2 - 10.1002/jbio.202400219
DO - 10.1002/jbio.202400219
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C2 - 39396931
AN - SCOPUS:85206155351
SN - 1864-063X
JO - Journal of Biophotonics
JF - Journal of Biophotonics
ER -