TY - JOUR
T1 - Novel boracycles from 2-amino-2-methylpropan-1-ol and borane methyl sulfide
T2 - Synthesis and X-ray crystal structures
AU - Baum, Ofir
AU - Goldberg, Israel
AU - Srebnik, Morris
N1 - Funding Information:
This research was supported in part by the Alex Grass Center for Drug Design and Synthesis of Novel Therapeutics, and by David R. Bloom Center of Pharmacy. O.B. thanks the Hebrew University of Jerusalem for the fellowships.
PY - 2006/4/15
Y1 - 2006/4/15
N2 - On reacting the simple 1,2-amino alcohol: 2-amino-2-methylpropan-1-ol, with borane methyl sulfide (BMS), the expected five member oxazaborolidine ring is not obtained. Instead, two polycyclic structures with trigonal boron atoms 6 and 7 were obtained, and their structure were determined by X-ray crystallography. Compound 6 was obtained in 39% yield and compound 7 was obtained in 7% yield.
AB - On reacting the simple 1,2-amino alcohol: 2-amino-2-methylpropan-1-ol, with borane methyl sulfide (BMS), the expected five member oxazaborolidine ring is not obtained. Instead, two polycyclic structures with trigonal boron atoms 6 and 7 were obtained, and their structure were determined by X-ray crystallography. Compound 6 was obtained in 39% yield and compound 7 was obtained in 7% yield.
KW - Boranes methyl sulfide
KW - Crystal structure
KW - Oxazaborolidine
UR - http://www.scopus.com/inward/record.url?scp=33645418027&partnerID=8YFLogxK
U2 - 10.1016/j.jorganchem.2006.01.003
DO - 10.1016/j.jorganchem.2006.01.003
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AN - SCOPUS:33645418027
SN - 0022-328X
VL - 691
SP - 1993
EP - 1997
JO - Journal of Organometallic Chemistry
JF - Journal of Organometallic Chemistry
IS - 9
ER -