TY - JOUR
T1 - Noninvasive Determination of Neonatal Hyperbilirubinemia
T2 - Standardization for Variation in Skin Color
AU - Linder, Nehama
AU - Regev, Aryeh
AU - Gazit, Gal
AU - Carplus, Michael
AU - Mandelberg, Avigdor
AU - Tamir, Israel
AU - Reichman, Brian
PY - 1994/5
Y1 - 1994/5
N2 - The estimation of plasma bilirubin concentration in neonates, using a transcutaneous, noninvasive jaundice meter, is significantly affected by many factors, such as gestatfonal age, birthweight, phototherapy, and skin pigmentation. In an attempt to minimize the influence of skin color and hence circumvent the need for standardization curves for different ethnic populations, we obtained noninvasive jaundice meter readings from the infant's midsternum within 4 hours of birth and subtracted this measurement from subsequent reading in infants with hyperbilirubinemia. These results were correlated with simultaneous plasma bilirubin determinations. By this method, a single standardization curve and improved sensitivity, specificity, and predictive values for the noninvasive determination of neonatal hyperbilirubinemia in a population of mixed ethnic origin was obtained.
AB - The estimation of plasma bilirubin concentration in neonates, using a transcutaneous, noninvasive jaundice meter, is significantly affected by many factors, such as gestatfonal age, birthweight, phototherapy, and skin pigmentation. In an attempt to minimize the influence of skin color and hence circumvent the need for standardization curves for different ethnic populations, we obtained noninvasive jaundice meter readings from the infant's midsternum within 4 hours of birth and subtracted this measurement from subsequent reading in infants with hyperbilirubinemia. These results were correlated with simultaneous plasma bilirubin determinations. By this method, a single standardization curve and improved sensitivity, specificity, and predictive values for the noninvasive determination of neonatal hyperbilirubinemia in a population of mixed ethnic origin was obtained.
UR - http://www.scopus.com/inward/record.url?scp=0028321573&partnerID=8YFLogxK
U2 - 10.1055/s-2008-1040751
DO - 10.1055/s-2008-1040751
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AN - SCOPUS:0028321573
SN - 0735-1631
VL - 11
SP - 223
EP - 225
JO - American Journal of Perinatology
JF - American Journal of Perinatology
IS - 3
ER -