|Number of pages||8|
|Journal||American Journal of Otolaryngology - Head and Neck Medicine and Surgery|
|State||Published - 1997|
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In: American Journal of Otolaryngology - Head and Neck Medicine and Surgery, Vol. 18, No. 6, 1997, p. 367-374.
Research output: Contribution to journal › Review article › peer-review
TY - JOUR
T1 - Noncutaneous cavernous hemangiomas of the head and neck
AU - Shpitzer, Thomas
AU - Noyek, Arnold M.
AU - Witterick, Ian
AU - Kassel, Ted
AU - Ichise, Masanori
AU - Gullane, Patrick
AU - Neligan, Peter
AU - Freeman, Jeremy
N1 - Funding Information: Hemangiomas are the most common congenital lesions in humans and represent the most frequent benign tumor in infants and children. Seventy-five percent of hemangiomas are present at birth, whereas 85% are noted by the age of 1 year. Although the head and neck region represents only 14% of the body surface area, 65% of hemangiomas arise in this location.‘J Hemangiomas are composed of a proliferation of normal-or abnormal-appearing blood vessels lined by endothelial cells (post capillary venous sinusoids). Histologically, cavernous hemangiomas are composed of a great number of large vascular channels lined with one layer of endothelial cells separated by fibrous septae. In the majority of cases, a cavernous hemangioma is associated with an From the Departments of Otolaryngology and Medical Imagine, Mount Sinai Hospital, Head and Neck Oncoloav Program, Toronto; and Department of Otolaryngology, and Division of Plastic Suraerv. The Toronto Hosoital Head and Neck Program, Ur%versity of Toronto, Ontario, Canada. Supported by The Tauba and Solomon Spiro Family Foundation (in memory of Max Tanenbaum), Toronto, Ontario; Saul A. Silverman Family Foundation as an Isabel Silverman Canada-International Scientific Exchange Program (CISEPO Canada-Israel) Project, Toronto. Ontario: Temmv Latner/Dvnacare. Toronto. OnE;t$adjnd Belmont Construction, Toronto, Ontario, Presented at the 4th International Conference on Head and Neck Cancer, Toronto, Ontario, Canada, July 28 to August 1,1996. Address reprint requests to Thomas Shpitzer, MD, c/o Peter Neligan, MD, The Toronto Hospital, General Division-EN 1 O-236,200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada. Copyright 0 1997 by W.B. Saunders Company 0196-0709/97/l 806-0001$5.00/O overlying capillary component that is histologically composed of small, thin-walled vessels of capillary size that are lined by a single layer of flattened or plump endothelial cells. In turn, these are usually surrounded by a discontinuous layer of pericytes and reticular fibers.3-5 Clinically, cavernous hemangiomas present as purplish, discolored lesions. They are typically soft, poorly defined, and readily blanch with compression. They have been likened to a “bag of worms.” The lesion may expand and darken with crying, agitation, or placement in a dependent position. 3*4,6C avernous hemangiomas occur in the liver, skeletal muscle, and some structures of the head and neck. Although uncommon in the head and neck, it has a predilection for the parotid gland, tongue, and larynx and rarely in other structures such as the mandible.7s8 The purpose of this study is to review the clinical and imaging diagnosis of cavernous hemangiomas as well as their treatment. In addition, several illustrative cases are presented.
PY - 1997
Y1 - 1997
UR - http://www.scopus.com/inward/record.url?scp=0030657976&partnerID=8YFLogxK
U2 - 10.1016/S0196-0709(97)90055-7
DO - 10.1016/S0196-0709(97)90055-7
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???
C2 - 9395011
AN - SCOPUS:0030657976
SN - 0196-0709
VL - 18
SP - 367
EP - 374
JO - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
JF - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
IS - 6