Regulatory sequences used in plasmids for naked DNA vaccination can modulate cytokine production in vivo. We demonstrate here that injection of plasmid DNA can suppress the prototypic T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis, by inducing IFN-γ.
|Number of pages||8|
|State||Published - 1999|
- Experimental autoimmune encephalomyelitis
- Gene therapy
- Multiple sclerosis