Nomenclature and Definition of Atrophic Lesions in Small Bowel Capsule Endoscopy: A Delphi Consensus Statement of the International CApsule endoscopy REsearch (I-CARE) Group

Luca Elli*, Beatrice Marinoni, Reena Sidhu, Christian Bojarski, Federica Branchi, Gian Eugenio Tontini, Stefania Chetcuti Zammit, Sherine Khater, Rami Eliakim, Emanuele Rondonotti, Jean Cristhophe Saurin, Mauro Bruno, Juliane Buchkremer, Sergio Cadoni, Flaminia Cavallaro, Xavier Dray, Pierre Ellul, Ignacio Fernandez Urien, Martin Keuchel, Uri KopylovAnastasios Koulaouzidis, Romain Leenhardt, Peter Baltes, Hanneke Beaumont, Clelia Marmo, Deirdre McNamara, Alessandro Mussetto, Artur Nemeth, Enrique Perez Cuadrado Robles, Guillame Perrod, Gabriel Rahmi, Maria Elena Riccioni, Alexander Robertson, Cristiano Spada, Ervin Toth, Konstantinos Triantafyllou, Gabriele Wurm Johansson, Alessandro Rimondi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

(1) Background: Villous atrophy is an indication for small bowel capsule endoscopy (SBCE). However, SBCE findings are not described uniformly and atrophic features are sometimes not recognized; (2) Methods: The Delphi technique was employed to reach agreement among a panel of SBCE experts. The nomenclature and definitions of SBCE lesions suggesting the presence of atrophy were decided in a core group of 10 experts. Four images of each lesion were chosen from a large SBCE database and agreement on the correspondence between the picture and the definition was evaluated using the Delphi method in a broadened group of 36 experts. All images corresponded to histologically proven mucosal atrophy; (3) Results: Four types of atrophic lesions were identified: mosaicism, scalloping, folds reduction, and granular mucosa. The core group succeeded in reaching agreement on the nomenclature and the descriptions of these items. Consensus in matching the agreed definitions for the proposed set of images was met for mosaicism (88.9% in the first round), scalloping (97.2% in the first round), and folds reduction (94.4% in the first round), but granular mucosa failed to achieve consensus (75.0% in the third round); (4) Conclusions: Consensus among SBCE experts on atrophic lesions was met for the first time. Mosaicism, scalloping, and folds reduction are the most reliable signs, while the description of granular mucosa remains uncertain.

Original languageEnglish
Article number1704
JournalDiagnostics
Volume12
Issue number7
DOIs
StatePublished - Jul 2022

Keywords

  • consensus
  • small bowel atrophy
  • video-capsule enteroscopy

Fingerprint

Dive into the research topics of 'Nomenclature and Definition of Atrophic Lesions in Small Bowel Capsule Endoscopy: A Delphi Consensus Statement of the International CApsule endoscopy REsearch (I-CARE) Group'. Together they form a unique fingerprint.

Cite this