Nodular vasculitis associated with propylthiouracil therapy

D. Wolf*, A. Ben-Yehuda, E. Okon, Y. Naparstek

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Cutaneous vasculitis is a rare complication of propylthiouracil therapy. We describe a patient who presented with lower extremity subcutaneous nodules, hemorrhagic bullae, and necrotic ulcers during treatment with this agent. Examination of a skin biopsy specimen revealed nodular vasculitis. This type of vasculitis has not been described in association with propylthiouracil therapy before. Nodular vasculitis not associated with the drug is characterized by a chronic protracted course, whereas in the patient reported the lesions rapidly regressed when use of the drug was discontinued.

Original languageEnglish
Pages (from-to)253-255
Number of pages3
JournalCutis
Volume49
Issue number4
StatePublished - 1992
Externally publishedYes

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