Nodular cutaneous amyloidosis

H. Trau*, D. Shpiro, M. Schewach-Millet, M. Pras, F. Prelli, B. Frangione

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A nodular cutaneous amyloidosis biopsy specimen from a solitary nodule of a 75-year-old patient was characterized by amino terminal sequence analysis and was proved to be derived from immunoglobulin κ(III) light chain. Five years after the diagnosis of amyloidosis in the skin was made, a rectal biopsy demonstrated amyloid deposits in a blood vessel. It is suggested that nodular cutaneous amyloidosis is a slowly progressive systemic disease of the AL type, that manifest itself mainly in the skin.

Original languageEnglish
Pages (from-to)414-417
Number of pages4
JournalAmerican Journal of Dermatopathology
Issue number4
StatePublished - 1991
Externally publishedYes


  • Amyloidosis
  • Nodule


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