Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

René S. Kahn; Michael Davidson; Jack Hirschowitz; Robert G. Stern; Bonnie M. David; Steve Gabriel; Clare Moore; Kenneth L. Davis

doi:10.1016/0165-1781(92)90107-E

Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

René S. Kahn, Michael Davidson, Jack Hirschowitz, Robert G. Stern, Bonnie M. David, Steve Gabriel, Clare Moore, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

Original language	English
Pages (from-to)	155-161
Number of pages	7
Journal	Psychiatry Research
Volume	41
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(92)90107-E
State	Published - Feb 1992
Externally published	Yes

Keywords

Psychoendocrinology
dopamine
hormones
serotonin

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-1781(92)90107-E

Cite this

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title = "Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects",

abstract = "Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.",

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AU - Davidson, Michael

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AU - Stern, Robert G.

AU - David, Bonnie M.

AU - Gabriel, Steve

AU - Moore, Clare

AU - Davis, Kenneth L.

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AB - Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

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KW - dopamine

KW - hormones

KW - serotonin

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Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

Abstract

Keywords

UN SDGs

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