Nociceptive circling and naloxone

R. Rabinowitz; N. Shlesinger; A. D. Korczyn

doi:10.1016/S0031-6989(83)80025-3

Nociceptive circling and naloxone

R. Rabinowitz, N. Shlesinger, A. D. Korczyn^*

^*Corresponding author for this work

Physiology Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

Under suitable conditions, mice exhibit rotatory behaviour, with a direction preference. Noxious electric stimulation to the feet of mice was found to increase significantly the rate of turning, as well as the ratio between circling in the preferred and in the opposite direction (the latter change was not significant statistically). Naloxone injected prior to the stimulation period tended to reverse the effects of the stimulation. These facts may imply that enkephalins are released during this stimulation and influence rotatory behaviour.

Original language	English
Pages (from-to)	963-967
Number of pages	5
Journal	Pharmacological Research Communications
Volume	15
Issue number	10
DOIs	https://doi.org/10.1016/S0031-6989(83)80025-3
State	Published - Nov 1983

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10.1016/S0031-6989(83)80025-3

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title = "Nociceptive circling and naloxone",

abstract = "Under suitable conditions, mice exhibit rotatory behaviour, with a direction preference. Noxious electric stimulation to the feet of mice was found to increase significantly the rate of turning, as well as the ratio between circling in the preferred and in the opposite direction (the latter change was not significant statistically). Naloxone injected prior to the stimulation period tended to reverse the effects of the stimulation. These facts may imply that enkephalins are released during this stimulation and influence rotatory behaviour.",

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year = "1983",

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AU - Shlesinger, N.

AU - Korczyn, A. D.

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N2 - Under suitable conditions, mice exhibit rotatory behaviour, with a direction preference. Noxious electric stimulation to the feet of mice was found to increase significantly the rate of turning, as well as the ratio between circling in the preferred and in the opposite direction (the latter change was not significant statistically). Naloxone injected prior to the stimulation period tended to reverse the effects of the stimulation. These facts may imply that enkephalins are released during this stimulation and influence rotatory behaviour.

AB - Under suitable conditions, mice exhibit rotatory behaviour, with a direction preference. Noxious electric stimulation to the feet of mice was found to increase significantly the rate of turning, as well as the ratio between circling in the preferred and in the opposite direction (the latter change was not significant statistically). Naloxone injected prior to the stimulation period tended to reverse the effects of the stimulation. These facts may imply that enkephalins are released during this stimulation and influence rotatory behaviour.

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Nociceptive circling and naloxone

Abstract

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