No longer rare diseases and obstetric anesthesia

Eitan Mangoubi, Michal Y. Livne, Leonid A. Eidelman, Sharon Orbach-Zinger*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Purpose of reviewWith new medical technologies and changing life styles, maternal demographics has changes and consequently older and sicker women are becoming pregnant.In this review, we present these different high-risk parturient populations, which were once considered rare for the practicing obstetric anesthesiologist.Recent findingsWith lifestyle and medical advances, older and sicker women are getting pregnant. Older women are more prone to pregnancy complications. Cancer survivors are becoming pregnant and more pregnant women are being diagnosed with cancer. Previous neurological and cardiac conditions considered not compatible with pregnancy are now seen more frequently. As the rate of obesity increases so does the rate of obstructive sleep apnea, which is known to be associated with many adverse maternal and neonatal sequalae. Finally, increased use of both opioids and marijuana has led to increased number of pregnant women using these illicit substances.SummaryFuture research and implementation of international guidelines for management of these high-risk parturient population is necessary in order to reduce maternal and neonatal morbidity.

Original languageEnglish
Pages (from-to)271-277
Number of pages7
JournalCurrent Opinion in Anaesthesiology
Issue number3
StatePublished - 2019


  • cancer
  • cardiac disease
  • maternal age
  • multiple sclerosis
  • obstructive sleep apnea and opioid use


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