No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

Alessandro Serretti, Alberto Chiesa, Raffaella Calati, Isabelle Massat, Sylvie Linotte, Siegfried Kasper, Yves Lecrubier, Martin Fink, Irina Antonijevic, Carlos Forray, Lenore Snyder, Joseph Bollen, Joseph Zohar, Diana De Ronchi, Daniel Souery, Julien Mendlewicz

Research output: Contribution to journalArticlepeer-review

Abstract

In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.

Original languageEnglish
Pages (from-to)166-169
Number of pages4
JournalPsychiatry Research
Volume188
Issue number1
DOIs
StatePublished - 30 Jun 2011
Externally publishedYes

Keywords

  • Major depressive disorder
  • PTGS2
  • Response

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