No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

Alessandro Serretti; Alberto Chiesa; Raffaella Calati; Isabelle Massat; Sylvie Linotte; Siegfried Kasper; Yves Lecrubier; Martin Fink; Irina Antonijevic; Carlos Forray; Lenore Snyder; Joseph Bollen; Joseph Zohar; Diana De Ronchi; Daniel Souery; Julien Mendlewicz

doi:10.1016/j.psychres.2010.11.023

No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

Alessandro Serretti^*, Alberto Chiesa, Raffaella Calati, Isabelle Massat, Sylvie Linotte, Siegfried Kasper, Yves Lecrubier, Martin Fink, Irina Antonijevic, Carlos Forray, Lenore Snyder, Joseph Bollen, Joseph Zohar, Diana De Ronchi, Daniel Souery, Julien Mendlewicz

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.

Original language	English
Pages (from-to)	166-169
Number of pages	4
Journal	Psychiatry Research
Volume	188
Issue number	1
DOIs	https://doi.org/10.1016/j.psychres.2010.11.023
State	Published - 30 Jun 2011
Externally published	Yes

Keywords

Major depressive disorder
PTGS2
Response

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.psychres.2010.11.023

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Serretti, A., Chiesa, A., Calati, R., Massat, I., Linotte, S., Kasper, S., Lecrubier, Y., Fink, M., Antonijevic, I., Forray, C., Snyder, L., Bollen, J., Zohar, J., De Ronchi, D., Souery, D., & Mendlewicz, J. (2011). No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression. Psychiatry Research, 188(1), 166-169. https://doi.org/10.1016/j.psychres.2010.11.023

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title = "No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression",

abstract = "In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.",

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note = "Funding Information: This study was funded by an unrestricted grant for the Group for the Study of the Resistant Depression (GSRD) , by Lundbeck A/S and by the Belgian National Fund for Scientific Research ( FNRS; 3.4.530.07F ). ",

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Serretti, A, Chiesa, A, Calati, R, Massat, I, Linotte, S, Kasper, S, Lecrubier, Y, Fink, M, Antonijevic, I, Forray, C, Snyder, L, Bollen, J, Zohar, J, De Ronchi, D, Souery, D & Mendlewicz, J 2011, 'No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression', Psychiatry Research, vol. 188, no. 1, pp. 166-169. https://doi.org/10.1016/j.psychres.2010.11.023

TY - JOUR

T1 - No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

AU - Serretti, Alessandro

AU - Chiesa, Alberto

AU - Calati, Raffaella

AU - Massat, Isabelle

AU - Linotte, Sylvie

AU - Kasper, Siegfried

AU - Lecrubier, Yves

AU - Fink, Martin

AU - Antonijevic, Irina

AU - Forray, Carlos

AU - Snyder, Lenore

AU - Bollen, Joseph

AU - Zohar, Joseph

AU - De Ronchi, Diana

AU - Souery, Daniel

AU - Mendlewicz, Julien

N1 - Funding Information: This study was funded by an unrestricted grant for the Group for the Study of the Resistant Depression (GSRD) , by Lundbeck A/S and by the Belgian National Fund for Scientific Research ( FNRS; 3.4.530.07F ).

PY - 2011/6/30

Y1 - 2011/6/30

N2 - In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.

AB - In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.

KW - Major depressive disorder

KW - PTGS2

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SN - 0165-1781

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EP - 169

JO - Psychiatry Research

JF - Psychiatry Research

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ER -

No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

Abstract

Keywords

UN SDGs

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