No beneficial effects of human growth hormone therapy in normal ovulatory patients with a poor ovarian response to gonadotropins

Jacob Levron; Nathan Lewit; Yohanan Erlik; Joseph Itskovitz-Eldor

doi:10.1159/000292667

No beneficial effects of human growth hormone therapy in normal ovulatory patients with a poor ovarian response to gonadotropins

Jacob Levron, Nathan Lewit, Yohanan Erlik, Joseph Itskovitz-Eldor^*

^*Corresponding author for this work

Technion-Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We studied the effects of human growth hormone (hGH) in 7 in vitro fertilization (IVF) patients with normal ovulatory menstrual cycles who showed a low response to ovarian stimulation with follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG). Human growth hormone therapy had no significant effect on the number of days of gonadotropic stimulation, on the total amount of hMG administered, on the serum estradiol level on the day of human chorionic gonadotropin injection, or on the IVF outcome. Our preliminary results do not encourage the routine use of hGH to improve IVF outcome in normogonadotropic ovulatory patients who respond poorly to the standard FSH/hMG protocol.

Original language	English
Pages (from-to)	65-68
Number of pages	4
Journal	Gynecologic and Obstetric Investigation
Volume	35
Issue number	2
DOIs	https://doi.org/10.1159/000292667
State	Published - 1993
Externally published	Yes

Keywords

Growth hormone
In vitro fertilization
Ovarian stimulation

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10.1159/000292667

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abstract = "We studied the effects of human growth hormone (hGH) in 7 in vitro fertilization (IVF) patients with normal ovulatory menstrual cycles who showed a low response to ovarian stimulation with follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG). Human growth hormone therapy had no significant effect on the number of days of gonadotropic stimulation, on the total amount of hMG administered, on the serum estradiol level on the day of human chorionic gonadotropin injection, or on the IVF outcome. Our preliminary results do not encourage the routine use of hGH to improve IVF outcome in normogonadotropic ovulatory patients who respond poorly to the standard FSH/hMG protocol.",

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AU - Erlik, Yohanan

AU - Itskovitz-Eldor, Joseph

PY - 1993

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AB - We studied the effects of human growth hormone (hGH) in 7 in vitro fertilization (IVF) patients with normal ovulatory menstrual cycles who showed a low response to ovarian stimulation with follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG). Human growth hormone therapy had no significant effect on the number of days of gonadotropic stimulation, on the total amount of hMG administered, on the serum estradiol level on the day of human chorionic gonadotropin injection, or on the IVF outcome. Our preliminary results do not encourage the routine use of hGH to improve IVF outcome in normogonadotropic ovulatory patients who respond poorly to the standard FSH/hMG protocol.

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No beneficial effects of human growth hormone therapy in normal ovulatory patients with a poor ovarian response to gonadotropins

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