No beneficial effects of human growth hormone therapy in normal ovulatory patients with a poor ovarian response to gonadotropins

Jacob Levron, Nathan Lewit, Yohanan Erlik, Joseph Itskovitz-Eldor*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the effects of human growth hormone (hGH) in 7 in vitro fertilization (IVF) patients with normal ovulatory menstrual cycles who showed a low response to ovarian stimulation with follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG). Human growth hormone therapy had no significant effect on the number of days of gonadotropic stimulation, on the total amount of hMG administered, on the serum estradiol level on the day of human chorionic gonadotropin injection, or on the IVF outcome. Our preliminary results do not encourage the routine use of hGH to improve IVF outcome in normogonadotropic ovulatory patients who respond poorly to the standard FSH/hMG protocol.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalGynecologic and Obstetric Investigation
Volume35
Issue number2
DOIs
StatePublished - 1993
Externally publishedYes

Keywords

  • Growth hormone
  • In vitro fertilization
  • Ovarian stimulation

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