Nickel-catalysed direct α-olefination of alkyl substituted N-heteroarenes with alcohols

Jagadish Das, Mari Vellakkaran, Debasis Banerjee*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Catalytic α-olefination of alkylheteroarenes with primary alcohols via dehydrogenative coupling is presented. A simple nickel catalyst system stabilised by readily available nitrogen ligands enables a series of interesting E-configured vinylarenes (confirmed by X-ray crystal-structure analysis) to be synthesised in good to excellent yields with olefin/alkane selectivity of >20:1. Hydrogen and water are generated as byproducts and quantitative determination of H2 was performed.

Original languageEnglish
Pages (from-to)7530-7533
Number of pages4
JournalChemical Communications
Issue number52
StatePublished - 2019
Externally publishedYes


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