New Surgical Approach to Overcome the Inability of Injured Mammalian Axons to Grow Within Their Environment

Arieh Solomon, Sjana Ben-Bassat, Michael Belkin, Vered Lavie, Michal Schwartz

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We present a new method for creating conditions conducive to axonal growth in injured optic nerves of adult rabbits. The surgical approach consists of making a cavity in the adult rabbit optic nerve, into which a piece of nitrocellulose soaked with conditioned medium originating from regenerating fish optic nerves is implanted. In addition, daily irradiation (10 days, 5 min, 35 mW) with low energy He-Ne laser is carried out. Such a combined treatment may open a door to neurobiologists and clinicians, hoping to unravel the enigma of mammalian CNS regeneration.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalJournal of Neural Transplantation and Plasticity
Volume2
Issue number3-4
DOIs
StatePublished - 1991

Keywords

  • Regeneration
  • mammalian CNS
  • surgical approach

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