New insight into calcinosis of juvenile dermatomyositis: A study of composition and treatment

Masza Mukamel*, Gadi Horev, Marc Mimouni

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

125 Scopus citations

Abstract

Milk of calcium developed in 2 Children with juvenile dermatomyositis. The fluid of the collection contained macrophages, interleukin-6, IL-1, and tumor necrosis factor. The patient who had dystrophic calcinosis had a dramatic improvement with the introduction of alendronate. These findings suggest that calcinosis of juvenile dermatomyositis may be mediated by activated macrophages and that alendronate can be an effective treatment for this condition.

Original languageEnglish
Pages (from-to)763-766
Number of pages4
JournalJournal of Pediatrics
Volume138
Issue number5
DOIs
StatePublished - 2001

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