Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio among patients with vestibular neuritis

Sagit Shushan, Shay Shemesh, Omer J. Ungar, Oren Cavel, Ophir Handzel, Sharon Ovnat Tamir, Yahav Oron

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To compare the level of the inflammatory markers (IM) neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) among healthy subjects and those presenting with vestibular neuritis (VN). Methods: A cross-sectional retrospective study was conducted in a tertiary hospital setting. The medical records of patients (20-60 years old) who were hospitalized between the years 2005 and 2014 with the diagnosis of VN were retrieved. Inclusion criteria were: (1) acute vertigo lasting for at least 24 h, (2) absence of auditory complaints, (3) presence of horizontal unidirectional nystagmus during physical examination, (4) absence of neurological symptoms or signs. The levels of the IM were compared with levels reported among two large cohorts of healthy subjects, within the same age range. Results: A statistically significant difference was found between the levels of NLR in VN subjects compared with controls, with higher levels of NLR in VN subjects (p < 0.001), while no significant difference was found between both groups concerning the levels of PLR. Conclusion: Higher levels of IM were found among VN patients, with significantly higher levels of NLR, but not PLR. This may suggest a possible inflammatory etiology of VN.

Original languageEnglish
Pages (from-to)304-308
Number of pages5
JournalORL
Volume81
Issue number5-6
DOIs
StatePublished - 1 Nov 2019
Externally publishedYes

Keywords

  • Inflammatory markers
  • Neuritis
  • Vertigo

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