@article{3b229da45dc341d8823bbcbc15b7f896,
title = "Neurotransmitter-caused increase in [3H]inositol incorporation into phosphatidylinositol de novo synthesis vs exchange",
abstract = "[3H]inositol and 32Pi were simultaneously incorporated into rat parotid phosphatidylinositol. The ratio of [3H]/32Pi incorporation dropped dramatically following stimulation with muscarinic or α-adrenergic agonists and returned to control values following the addition of appropriate antagonists. The drop in [3H]/32Pi ratio can be explained by a rapid increase in de- novo synthesis of phosphatidylinositol following its receptor-mediated breakdown. The change in this ratio also provided evidence for the existence of CDP-DG + inositol ⇄ phosphatidylinositol exchange reaction in the intact tissue.",
keywords = "Phosphatidylinositol αAdrenergic Muscarinic Receptors Rat parotid",
author = "Monica Lupu and Yoram Oron",
note = "Funding Information: This project was supported in part by a SchreiberF oundation grant.",
year = "1983",
month = oct,
day = "3",
doi = "10.1016/0014-5793(83)81064-3",
language = "אנגלית",
volume = "162",
pages = "133--136",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "John Wiley and Sons Inc.",
number = "1",
}