TY - JOUR
T1 - Neurophysin biosynthesis
T2 - Conversion of a putative precursor during axonal transport
AU - Gainer, Harold
AU - Sarne, Yosef
AU - Brownstein, Michael J.
PY - 1977
Y1 - 1977
N2 - [35S]Cysteine injected adjacent to the supraoptic nucleus of the rat is rapidly incorporated into a 20,000-dalton protein that, in time, is converted to a 12,000-dalton labeled protein, neurophysin. This putative precursor of neurophysin appears to be synthesized in the supraoptic nucleus and transformed to neurophysin and related peptides during axonal transport to the neurohypophysis.
AB - [35S]Cysteine injected adjacent to the supraoptic nucleus of the rat is rapidly incorporated into a 20,000-dalton protein that, in time, is converted to a 12,000-dalton labeled protein, neurophysin. This putative precursor of neurophysin appears to be synthesized in the supraoptic nucleus and transformed to neurophysin and related peptides during axonal transport to the neurohypophysis.
UR - http://www.scopus.com/inward/record.url?scp=0017325218&partnerID=8YFLogxK
U2 - 10.1126/science.65791
DO - 10.1126/science.65791
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C2 - 65791
AN - SCOPUS:0017325218
SN - 0036-8075
VL - 195
SP - 1354
EP - 1356
JO - Science
JF - Science
IS - 4284
ER -