Neuroendocrine study of a male infant with septo-optic dysplasia

L. Sirota, Z. Dickerman, Z. Laron, R. Weitz, F. Dulitzky

Research output: Contribution to journalArticlepeer-review


Septo-optic dysplasia includes abnormalities of the optic nerves and tracts with absence of the septum pellucidum. Most of the recently reported patients were deficient in growth hormone. We describe a male infant with septo-optic dysplasia in whom extensive endocrine evaluation revealed central diabetes insipidus, hypothalamic hypothyroidism and combined (hypothalamic-pituitary) hypoadrenalism, along with normal pituitary growth hormone reserve. This is the first reported case of a patient with septo-optic dysplasia who underwent corticotropin-releasing factor and growth hormone-releasing hormone stimulation.

Original languageEnglish
Pages (from-to)745-749
Number of pages5
JournalIsrael Journal of Medical Sciences
Issue number9
StatePublished - 1985
Externally publishedYes


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