NetworkBLAST: Comparative analysis of protein networks

Maxim Kalaev*, Mike Smoot, Trey Ideker, Roded Sharan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The identification of protein complexes is a fundamental challenge in interpreting protein-protein interaction data. Cross-species analysis allows coping with the high levels of noise that are typical to these data. The NetworkBLAST web-server provides a platform for identifying protein complexes in protein-protein interaction networks. It can analyze a single network or two networks from different species. In the latter case, NetworkBLAST outputs a set of putative complexes that are evolutionarily conserved across the two networks.

Original languageEnglish
Pages (from-to)594-596
Number of pages3
Issue number4
StatePublished - Feb 2008


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