Nephrocalcinosis in pseudohypoaldosteronism and the effect of indomethacin therapy

Hanna Shalev, Melly Ohali, Oren Abramson, Moshe Phillip

Research output: Contribution to journalArticlepeer-review


We report four patients with pseudohypoaldosteronism, aged 5 months to 5 years. All patients had hypercalciuria and three had nephrocalcinosis. Two patients with nephrocalcinosis were treated with indomethacin. Polydipsia decreased and appetite and weight gain improved within 14 days of therapy. Hypercalciuria, polyuria, and creatinine clearance decreased 30% to 50% and urinary prostaglandin E2 levels decreased fourfold to eightfold. (J PEDIATR 1994;125:246-8).

Original languageEnglish
Pages (from-to)246-248
Number of pages3
JournalJournal of Pediatrics
Issue number2
StatePublished - Aug 1994


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