TY - JOUR
T1 - Neonatal herpes simplex virus infection and asymptomatic maternal infection
AU - Somekh, Eli
AU - Thanhauser, David
AU - Feder, Henry M.
AU - Brown, Zane A.
AU - Benedetti, Jacqueline
AU - Ashley, Rhoda
AU - Burchett, Sandra
AU - Selke, Stacey
AU - Berry, Sylvia
AU - Vontver, Louis A.
AU - Corey, Lawrence
PY - 1991/9/26
Y1 - 1991/9/26
N2 - To the Editor: The article by Brown et al. (May 2 issue)1 nicely demonstrated the significant difference in the incidence of neonatal infection with herpes simplex virus (HSV) between infants born to women with recently acquired asymptomatic genital HSV and those born to women with asymptomatic reactivation of HSV. The authors also demonstrated that the presence of maternal antibodies specific for HSV-2 but not for HSV-1 appeared to reduce the neonatal transmission of HSV-2. They state, “None of the 31 infants born to mothers with reactivation of HSV-2 infection in early labor subsequently had neonatal herpes.” This statement, although valid.
AB - To the Editor: The article by Brown et al. (May 2 issue)1 nicely demonstrated the significant difference in the incidence of neonatal infection with herpes simplex virus (HSV) between infants born to women with recently acquired asymptomatic genital HSV and those born to women with asymptomatic reactivation of HSV. The authors also demonstrated that the presence of maternal antibodies specific for HSV-2 but not for HSV-1 appeared to reduce the neonatal transmission of HSV-2. They state, “None of the 31 infants born to mothers with reactivation of HSV-2 infection in early labor subsequently had neonatal herpes.” This statement, although valid.
UR - http://www.scopus.com/inward/record.url?scp=0025943228&partnerID=8YFLogxK
U2 - 10.1056/NEJM199109263251314
DO - 10.1056/NEJM199109263251314
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C2 - 1652689
AN - SCOPUS:0025943228
SN - 0028-4793
VL - 325
SP - 965
EP - 966
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 13
ER -