Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations

Anna Reid; Sagit Ben Zekry; Mansi Turaga; Stephanie Tarazi; Jeroen J. Bax; Dee Dee Wang; Nicolo Piazza; Vinayak N. Bapat; Abdul Rahman Ihdayhid; João L. Cavalcante; Philipp Blanke; Jonathon Leipsic

doi:10.1016/j.jcmg.2020.09.027

Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations

Anna Reid, Sagit Ben Zekry, Mansi Turaga, Stephanie Tarazi, Jeroen J. Bax, Dee Dee Wang, Nicolo Piazza, Vinayak N. Bapat, Abdul Rahman Ihdayhid, João L. Cavalcante, Philipp Blanke, Jonathon Leipsic^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

85 Scopus citations

Abstract

With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo–left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-LVOT. A summary of expert-based recommendations about the overall risk of LVOT obstruction in different scenarios is presented along with the currently available methods to reduce the risk of LVOT obstruction and other post-procedural complications.

Original language	English
Pages (from-to)	854-866
Number of pages	13
Journal	JACC: Cardiovascular Imaging
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/j.jcmg.2020.09.027
State	Published - Apr 2021
Externally published	Yes

Keywords

LVOT
LVOT obstruction
neo-LVOT
transcatheter mitral valve replacement

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10.1016/j.jcmg.2020.09.027

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title = "Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations",

abstract = "With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo–left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-LVOT. A summary of expert-based recommendations about the overall risk of LVOT obstruction in different scenarios is presented along with the currently available methods to reduce the risk of LVOT obstruction and other post-procedural complications.",

keywords = "LVOT, LVOT obstruction, neo-LVOT, transcatheter mitral valve replacement",

author = "Anna Reid and {Ben Zekry}, Sagit and Mansi Turaga and Stephanie Tarazi and Bax, {Jeroen J.} and Wang, {Dee Dee} and Nicolo Piazza and Bapat, {Vinayak N.} and Ihdayhid, {Abdul Rahman} and Cavalcante, {Jo{\~a}o L.} and Philipp Blanke and Jonathon Leipsic",

note = "Publisher Copyright: {\textcopyright} 2021 American College of Cardiology Foundation",

year = "2021",

month = apr,

doi = "10.1016/j.jcmg.2020.09.027",

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AU - Turaga, Mansi

AU - Tarazi, Stephanie

AU - Bax, Jeroen J.

AU - Wang, Dee Dee

AU - Piazza, Nicolo

AU - Bapat, Vinayak N.

AU - Ihdayhid, Abdul Rahman

AU - Cavalcante, João L.

AU - Blanke, Philipp

AU - Leipsic, Jonathon

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Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations

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Keywords

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