Necrotizing granulomata in the lung preceding colonic involvement in 2 patients with Crohn's disease

Tiberiu Shulimzon; Jehudit Rozenman; Marina Perelman; Eytan Bardan; Issahar Ben-Dov

doi:10.1159/000092854

Necrotizing granulomata in the lung preceding colonic involvement in 2 patients with Crohn's disease

Tiberiu Shulimzon^*, Jehudit Rozenman, Marina Perelman, Eytan Bardan, Issahar Ben-Dov

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Extraintestinal involvement, including the chest, is common in the late course of Crohn's disease. We describe 2 female patients in whom the course of the disease was unique in two aspects: (1) each had a pulmonary mass with granulomatous inflammation and necrosis, and (2) these findings had preceded the colonic involvement by 5 years. This sequence supports some of the theories on the pathogenesis of Crohn's disease and on its possible relation with sarcoidosis, another idiopathic granulomatous disease.

Original language	English
Pages (from-to)	698-702
Number of pages	5
Journal	Respiration
Volume	74
Issue number	6
DOIs	https://doi.org/10.1159/000092854
State	Published - Nov 2007

Keywords

Crohn's disease
Extracolonic involvement
Inflammatory bowel disease
Sarcoidosis
Tuberculosis

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10.1159/000092854

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abstract = "Extraintestinal involvement, including the chest, is common in the late course of Crohn's disease. We describe 2 female patients in whom the course of the disease was unique in two aspects: (1) each had a pulmonary mass with granulomatous inflammation and necrosis, and (2) these findings had preceded the colonic involvement by 5 years. This sequence supports some of the theories on the pathogenesis of Crohn's disease and on its possible relation with sarcoidosis, another idiopathic granulomatous disease.",

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AU - Perelman, Marina

AU - Bardan, Eytan

AU - Ben-Dov, Issahar

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AB - Extraintestinal involvement, including the chest, is common in the late course of Crohn's disease. We describe 2 female patients in whom the course of the disease was unique in two aspects: (1) each had a pulmonary mass with granulomatous inflammation and necrosis, and (2) these findings had preceded the colonic involvement by 5 years. This sequence supports some of the theories on the pathogenesis of Crohn's disease and on its possible relation with sarcoidosis, another idiopathic granulomatous disease.

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KW - Extracolonic involvement

KW - Inflammatory bowel disease

KW - Sarcoidosis

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Necrotizing granulomata in the lung preceding colonic involvement in 2 patients with Crohn's disease

Abstract

Keywords

UN SDGs

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