Abstract
An 8-year-old child with familial Mediterranean fever exhibited signs of colchicine intoxication while receiving prophylactic doses of the drug. She developed gastrointestinal, central nervous system, cardiovascular and haematological disturbances. Over 2 months she had been drinking high doses of natural grapefruit juice which, combined with long-term colchicine therapy and a viral upper respiratory tract infection, increased her susceptibility to the drug. Conclusion: To the best of our knowledge, this is the first time colchicine intoxication in this age group has been described in the English literature.
| Original language | English |
|---|---|
| Pages (from-to) | 895-897 |
| Number of pages | 3 |
| Journal | European Journal of Pediatrics |
| Volume | 159 |
| Issue number | 12 |
| DOIs | |
| State | Published - 2000 |
| Externally published | Yes |
Keywords
- Colchicine intoxication
- Familial Mediterranean fever
- Grapefruit juice
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