Abstract
The major aim of this study is to determine the mode of inheritance of asymmetry of quantitative dermatoglyphic traits based on principal factors through the application of complex segregation (genetic model fitting) analyses on a large ethnically homogeneous sample of 500 Indian pedigrees (2435 individuals) of two generations. By segregation analysis of the traits- PC1_FA both Mendelian and Environmental models were rejected (<0.001) with the General model, i.e. that despite presence of significant inheritance (rejection of Environmental model), the nature of inheritance is more complex, than Mendelian one. Although a little genetic effect was observed due to familial correlations on asymmetry traits, no evidence was found of major gene contribution to be involved, but this does not contradict the notion postulated by several earlier authors1,2,17 that asymmetry (fluctuating) provides a measure of developmental instability in human.
| Translated title of the contribution | Inheritance of dermatoglyphic asymmetry in 500 Indian pedigrees: Complex segregation analysis |
|---|---|
| Original language | English |
| Pages (from-to) | 53-60 |
| Number of pages | 8 |
| Journal | Collegium Antropologicum |
| Volume | 36 |
| Issue number | 1 |
| State | Published - Mar 2012 |
Keywords
- Dermatoglyphic asymmetry
- Indian population
- Segregation analysis