TY - JOUR
T1 - Naproxen as an alternative to aspirin for the treatment of arthritis of rheumatic fever
T2 - A randomized trial
AU - Hashkes, Philip J.
AU - Tauber, Tsivia
AU - Somekh, Eli
AU - Brik, Riva
AU - Barash, Judith
AU - Mukamel, Masza
AU - Harel, Liora
AU - Lorber, Abraham
AU - Berkovitch, Matityahj
AU - Uziel, Yosef
N1 - Funding Information:
Supported in part by grant no. S/4507 from the Chief Scientist's Office of the Ministry of Health, Israel.
PY - 2003/9/1
Y1 - 2003/9/1
N2 - We performed a prospective, randomized, open-label equivalence study comparing the use of naproxen to aspirin in 33 patients with rheumatic fever. The mean time until resolution of arthritis was 2.9 ± 2.9 days in both groups. Liver enzyme elevations were more frequent in the aspirin group (P = .002). We conclude that naproxen is as effective, is easier to use, and is safer than aspirin in the treatment of the arthritis of rheumatic fever.
AB - We performed a prospective, randomized, open-label equivalence study comparing the use of naproxen to aspirin in 33 patients with rheumatic fever. The mean time until resolution of arthritis was 2.9 ± 2.9 days in both groups. Liver enzyme elevations were more frequent in the aspirin group (P = .002). We conclude that naproxen is as effective, is easier to use, and is safer than aspirin in the treatment of the arthritis of rheumatic fever.
UR - http://www.scopus.com/inward/record.url?scp=0141839057&partnerID=8YFLogxK
U2 - 10.1067/S0022-3476(03)00388-3
DO - 10.1067/S0022-3476(03)00388-3
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AN - SCOPUS:0141839057
SN - 0022-3476
VL - 143
SP - 399
EP - 401
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 3
ER -