TY - JOUR
T1 - Nanowiring of the catalytic site of novel molecular enzyme-metal hybrids to electrodes
AU - Dagan-Moscovich, Hila
AU - Cohen-Hadar, Noa
AU - Porat, Carmit
AU - Rishpon, Judith
AU - Shacham-Diamand, Yosi
AU - Freeman, Amihay
PY - 2007/4/19
Y1 - 2007/4/19
N2 - Directed deposition of silver on the surface of single, soluble enzyme molecules was made possible by controlled conjugation of new silver-reducing moieties to the surface of the enzyme molecule and their reaction with silver ions. Molecular enzyme-silver hybrids carrying low or high crystalline silver deposited on their surface were obtained, retaining their solubility and enzymatic activity. The feasibility of "wiring" of the active site of glucose oxidase-silver hybrid thus obtained to platinum electrode was readily demonstrated enabling glucose determination in the absence of oxygen.
AB - Directed deposition of silver on the surface of single, soluble enzyme molecules was made possible by controlled conjugation of new silver-reducing moieties to the surface of the enzyme molecule and their reaction with silver ions. Molecular enzyme-silver hybrids carrying low or high crystalline silver deposited on their surface were obtained, retaining their solubility and enzymatic activity. The feasibility of "wiring" of the active site of glucose oxidase-silver hybrid thus obtained to platinum electrode was readily demonstrated enabling glucose determination in the absence of oxygen.
UR - http://www.scopus.com/inward/record.url?scp=34247552209&partnerID=8YFLogxK
U2 - 10.1021/jp066100u
DO - 10.1021/jp066100u
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AN - SCOPUS:34247552209
SN - 1932-7447
VL - 111
SP - 5766
EP - 5769
JO - Journal of Physical Chemistry C
JF - Journal of Physical Chemistry C
IS - 15
ER -