Myelokathexis and monocytosis in a patient with gastric cancer

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Abstract

A 66-year-old patient developed leukocytosis, neutrophilia and monocytosis following surgery for gastric carcinoma. The polymorphonuclear cells showed a marked shift to the right and abnormally hypersegmented or pyknotic nuclei, whereas the monocytes were vacuolized. The bone marrow was hypcrccllular with an increased number of multilobed polymorphonuclear cells. This myeloid cell defect is compatible with the nuclear abnormalities described as myelokathexis. The combination of the nuclear abnormalities of the polymorphonuclear cells with persistent monocytosis suggests the possibility of a paraneoplastic variant of myelodysplasia.

Original languageEnglish
Pages (from-to)210-212
Number of pages3
JournalActa Haematologica
Volume87
Issue number4
DOIs
StatePublished - 1992
Externally publishedYes

Keywords

  • Carcinoma
  • Gastric
  • Leukocytosis
  • Monocytosis
  • Myelokathexis
  • Neutrophilia

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