Mycophenolate Mofetil for the Management of Autoimmune Bullous Diseases

Marina Eskin-Schwartz, Michael David, Daniel Mimouni

Research output: Contribution to journalReview articlepeer-review

Abstract

Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.

Original languageEnglish
Pages (from-to)309-315
Number of pages7
JournalImmunology and Allergy Clinics of North America
Volume32
Issue number2
DOIs
StatePublished - May 2012

Keywords

  • Autoimmune bullous diseases
  • Immunosuppression
  • Mycophenolate mofetil
  • Mycophenolic acid

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