TY - JOUR
T1 - Mycophenolate Mofetil for the Management of Autoimmune Bullous Diseases
AU - Eskin-Schwartz, Marina
AU - David, Michael
AU - Mimouni, Daniel
PY - 2012/5
Y1 - 2012/5
N2 - Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.
AB - Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.
KW - Autoimmune bullous diseases
KW - Immunosuppression
KW - Mycophenolate mofetil
KW - Mycophenolic acid
UR - http://www.scopus.com/inward/record.url?scp=84860467026&partnerID=8YFLogxK
U2 - 10.1016/j.iac.2012.04.010
DO - 10.1016/j.iac.2012.04.010
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AN - SCOPUS:84860467026
SN - 0889-8561
VL - 32
SP - 309
EP - 315
JO - Immunology and Allergy Clinics of North America
JF - Immunology and Allergy Clinics of North America
IS - 2
ER -
