TY - JOUR
T1 - Mycophenolate Mofetil for the Management of Autoimmune Bullous Diseases
AU - Eskin-Schwartz, Marina
AU - David, Michael
AU - Mimouni, Daniel
PY - 2011/10
Y1 - 2011/10
N2 - Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.
AB - Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.
KW - Autoimmune bullous diseases
KW - Immunosuppression
KW - Mycophenolate mofetil
KW - Mycophenolic acid
UR - http://www.scopus.com/inward/record.url?scp=80052883255&partnerID=8YFLogxK
U2 - 10.1016/j.det.2011.06.012
DO - 10.1016/j.det.2011.06.012
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AN - SCOPUS:80052883255
SN - 0733-8635
VL - 29
SP - 555
EP - 559
JO - Dermatologic Clinics
JF - Dermatologic Clinics
IS - 4
ER -