TY - JOUR
T1 - Mycobacteria and autoimmunity
AU - Shoenfeld, Yehuda
AU - Isenberg, David A.
N1 - Funding Information:
Y. Shoenfeld was supported in part by grants of the Israeli Academy for Sciences, the Basic Foundation and a grant of the Chief Scientist of Ministry of Health.
PY - 1988
Y1 - 1988
N2 - Autoimmune disease appears to be influenced by multiple factors, including the genetic, hormonal and immunological status of the individual. However, environmental agents have also been implicated in the initiation of these diseases, and mycobacteria have for a long time been listed among these agents. In this article, Yehuda Shoenfeld and David Isenberg summarize the current evidence linking mycobacterial infection with autoimmune disease. Based on considerable evidence of molecular mimicry between mycobacteria and host antigens, they postulate possible ways in which mycobacteria may precipitate autoimmune disease.
AB - Autoimmune disease appears to be influenced by multiple factors, including the genetic, hormonal and immunological status of the individual. However, environmental agents have also been implicated in the initiation of these diseases, and mycobacteria have for a long time been listed among these agents. In this article, Yehuda Shoenfeld and David Isenberg summarize the current evidence linking mycobacterial infection with autoimmune disease. Based on considerable evidence of molecular mimicry between mycobacteria and host antigens, they postulate possible ways in which mycobacteria may precipitate autoimmune disease.
UR - http://www.scopus.com/inward/record.url?scp=0023916778&partnerID=8YFLogxK
U2 - 10.1016/0167-5699(88)91294-7
DO - 10.1016/0167-5699(88)91294-7
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AN - SCOPUS:0023916778
SN - 0167-5699
VL - 9
SP - 178
EP - 182
JO - Immunology Today
JF - Immunology Today
IS - 6
ER -