TY - JOUR
T1 - Mycobacteria and autoimmunity
AU - Shoenfeld, Yehuda
AU - Isenberg, David A.
N1 - Funding Information:
Y. Shoenfeld was supported in part by grants of the Israeli Academy for Sciences, the Basic Foundation and a grant of the Chief Scientist of Ministry of Health.
PY - 1988
Y1 - 1988
N2 - Autoimmune disease appears to be influenced by multiple factors, including the genetic, hormonal and immunological status of the individual. However, environmental agents have also been implicated in the initiation of these diseases, and mycobacteria have for a long time been listed among these agents. In this article, Yehuda Shoenfeld and David Isenberg summarize the current evidence linking mycobacterial infection with autoimmune disease. Based on considerable evidence of molecular mimicry between mycobacteria and host antigens, they postulate possible ways in which mycobacteria may precipitate autoimmune disease.
AB - Autoimmune disease appears to be influenced by multiple factors, including the genetic, hormonal and immunological status of the individual. However, environmental agents have also been implicated in the initiation of these diseases, and mycobacteria have for a long time been listed among these agents. In this article, Yehuda Shoenfeld and David Isenberg summarize the current evidence linking mycobacterial infection with autoimmune disease. Based on considerable evidence of molecular mimicry between mycobacteria and host antigens, they postulate possible ways in which mycobacteria may precipitate autoimmune disease.
UR - http://www.scopus.com/inward/record.url?scp=45549121626&partnerID=8YFLogxK
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AN - SCOPUS:45549121626
SN - 1471-4906
VL - 9
SP - 182
EP - 183
JO - Trends in Immunology
JF - Trends in Immunology
IS - 1-12
ER -