Covalent binding of metabolically activated aflatoxin B1 (AFB1) to transforming DNA of Pneumococcus caused a decrease in transforming activity and induced mutations to antibiotic resistance in recipients. The 2 effects were proportional, in vitro, to the covalent bnding levels of AFB1 to pneumococcal DNA.
|Number of pages||10|
|Journal||Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis|
|State||Published - Jan 1983|