Multiple sclerosis - In need of a critical reappraisal

I. Steiner*, I. Wirguin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Multiple sclerosis (MS) is a disease that currently defies clinical and scientific definitions. Despite intensive clinical and basic research, very little is known about its possible cause(s) or pathogenesis, and the course and prognosis of MS practically remain unchanged. The aim of the present article is to outline some of the reasons for the constant failure to improve the therapy of MS. It also attempts to offer several guidelines which may enable a fresh and different approach to this devastating condition. (C) 2000 Harcourt Publishers Ltd.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalMedical Hypotheses
Issue number1
StatePublished - Jan 2000
Externally publishedYes


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