Multiple sclerosis and anti-phospholipid syndrome - One or two diseases?

Anat Achiron*, Mathilda Mandel, Yehuda Shoenfeld

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Multiple sclerosis is an autoimmune central nervous system disease that affects young adults and causes inflammation, demyelination and axonal loss. Within the common relapsing-remitting course of the disease patients develop various neurological symptoms that lead to significant disability overtime. The anti-phospholipid syndrome, similarly to multiple sclerosis, appears in young adults and is characterized by thromboembolic events and pregnancy complications. The overlay between these two diseases and the ability to correctly diagnose or differentiate between them is sometimes difficult. The current review approaches this problem and discusses whether multiple sclerosis and anti-phospholipid syndrome are actually one or two diseases.

Original languageEnglish
Pages (from-to)724-726
Number of pages3
Issue number10
StatePublished - Oct 2004


  • Anti-cardiolopin antibodies
  • Antiphospholipid syndrome
  • Lupus anticoagulant
  • Multiple sclerosis


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