Multilocus sequence typing (MLST) of Escherichia coli O78 strains

Roni S. Adiri, Uri Gophna, Eliora Z. Ron*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Strains of Escherichia coli serotype O78 are associated with many diseases, including invasive infections, in humans and farm animals. The clonal relationship between strains from different hosts is therefore important for assessing the risk of zoonotic infections. Here we propose a multilocus sequence typing scheme for E. coli, based on six housekeeping genes. Preliminary, but significant, results indicate that clonal division in E. coli O78 strains is host independent, and closely related clones reside in different hosts. There was a positive correlation between virulence and clonal origin.

Original languageEnglish
Pages (from-to)199-203
Number of pages5
JournalFEMS Microbiology Letters
Volume222
Issue number2
DOIs
StatePublished - 28 May 2003

Funding

FundersFunder number
Israel Center for Emerging Diseases
Manja and Morris Leigh Chair for Biophysics and Biotechnology
European Commission

    Keywords

    • Avian colisepticemia
    • Bacterial virulence
    • Multilocus sequence typing
    • Newborn meningitis
    • Sepsis
    • Serotype O78

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