Multidisciplinary management of breast cancer brain metastases

Timothy M. Zagar, Amanda E.D. Van Swearingen, Orit Kaidar-Person, Matthew G. Ewend, Carey K. Anders

Research output: Contribution to journalReview articlepeer-review


This review summarizes the most up-to-date approach to the multidisciplinary management of patients with breast cancer brain metastases. A brief overview of the epidemiology and biology of breast cancer brain metastasis is provided. The perspectives of radiation oncology, neurosurgery, and medical oncology-and landmark studies from each discipline-are all discussed. We also offer practical tips to help guide the treating physician, including data on antiseizure medications. Finally, we introduce the concept of a multidisciplinary clinic that combines input from medical and radiation oncology, neurosurgery, and support services, which we developed at the University of North Carolina as a coordinated and optimal approach to the management of patients with this complex disease.

Original languageEnglish
Issue number10
StatePublished - 1 Oct 2016
Externally publishedYes


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