TY - JOUR
T1 - MRI-based diagnosis and treatment of pediatric brain tumors
T2 - is tissue sample always needed?
AU - Soleman, Jehuda
AU - Dvir, Rina
AU - Ben-Sira, Liat
AU - Yalon, Michal
AU - Boop, Frederick
AU - Constantini, Shlomi
AU - Roth, Jonathan
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021/5
Y1 - 2021/5
N2 - Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological diagnosis. To date, many treatment regimens are based on molecular biology. The scope of this article is to discuss the role of diagnosis and further treatment of PBTs based solely on MRI features, in light of the latest treatment protocols. Typical MRI findings and indications for surgical biopsy of these lesions are described.
AB - Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological diagnosis. To date, many treatment regimens are based on molecular biology. The scope of this article is to discuss the role of diagnosis and further treatment of PBTs based solely on MRI features, in light of the latest treatment protocols. Typical MRI findings and indications for surgical biopsy of these lesions are described.
KW - Image-based diagnosis
KW - Magnetic resonance imaging
KW - Pediatric brain tumors
KW - Pediatric neuroradiology
KW - Pediatric neurosurgery
KW - Surgical biopsy
UR - http://www.scopus.com/inward/record.url?scp=85103614573&partnerID=8YFLogxK
U2 - 10.1007/s00381-021-05148-1
DO - 10.1007/s00381-021-05148-1
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C2 - 33821340
AN - SCOPUS:85103614573
SN - 0256-7040
VL - 37
SP - 1449
EP - 1459
JO - Child's Nervous System
JF - Child's Nervous System
IS - 5
ER -
