TY - JOUR
T1 - Morphological evaluation of lateral ventricles of fetuses with ventriculomegaly by three-dimensional ultrasonography and magnetic resonance imaging
T2 - Correlation with etiology
AU - Haratz, Karina Krajden
AU - Nardozza, Luciano Marcondes Mac Hado
AU - De Oliveira, Patrícia Soares
AU - Rolo, Liliam Cristine
AU - Milani, Hérbene José Figuinha
AU - De Sá Barreto, Enoch Quinderé
AU - Araujo Júnior, Edward
AU - Ajzen, Sérgio Aron
AU - Moron, Antonio Fernandes
PY - 2011/8
Y1 - 2011/8
N2 - Purpose To evaluate morphology of lateral ventricles of ventriculomegaly/hydrocephaly fetuses using 3D-sonography by virtual organ computer-aided analysis (VOCAL) technique and magnetic resonance imaging (MRI) and verify morphologic patterns related to etiology. Methods Seventeen fetuses presenting with ventricular enlargement (atria > 10 mm) were evaluated. 3D datasets were acquired from a coronal reference plane and post-processed by the rotational imaging using VOCAL 30°. MRI study was analyzed in the three plans in all sequences. Morphologic aspects such as global shape, anterior, posterior and inferior horn characteristics, wall irregularities and deformities were analyzed and related to etiology factor. Results Twenty-nine percent of the cases were secondary to Arnold-Chiari syndrome and presented with global dilation of the three-horns. Cases related to aqueduct stenosis presented with ependymal rupture and wall irregularities in advanced cases. Corpus callosum agenesis cases presented with small ventricular volumes, thin shape, normal or slightly enlarged anterior and inferior horns with dilation restricted to posterior horn. Cases related to trisomy 18 and cytomegalovirus presented irregular ventricular walls associated with anomalous ventricular shapes, suggesting parenchymal destruction. Conclusion Ventricular morphology evaluation gives important information on etiology of ventricular enlargement, supporting prognosis prediction and decision making process of the aVected fetuses and their families.
AB - Purpose To evaluate morphology of lateral ventricles of ventriculomegaly/hydrocephaly fetuses using 3D-sonography by virtual organ computer-aided analysis (VOCAL) technique and magnetic resonance imaging (MRI) and verify morphologic patterns related to etiology. Methods Seventeen fetuses presenting with ventricular enlargement (atria > 10 mm) were evaluated. 3D datasets were acquired from a coronal reference plane and post-processed by the rotational imaging using VOCAL 30°. MRI study was analyzed in the three plans in all sequences. Morphologic aspects such as global shape, anterior, posterior and inferior horn characteristics, wall irregularities and deformities were analyzed and related to etiology factor. Results Twenty-nine percent of the cases were secondary to Arnold-Chiari syndrome and presented with global dilation of the three-horns. Cases related to aqueduct stenosis presented with ependymal rupture and wall irregularities in advanced cases. Corpus callosum agenesis cases presented with small ventricular volumes, thin shape, normal or slightly enlarged anterior and inferior horns with dilation restricted to posterior horn. Cases related to trisomy 18 and cytomegalovirus presented irregular ventricular walls associated with anomalous ventricular shapes, suggesting parenchymal destruction. Conclusion Ventricular morphology evaluation gives important information on etiology of ventricular enlargement, supporting prognosis prediction and decision making process of the aVected fetuses and their families.
KW - Etiology
KW - Fetuses
KW - Magnetic resonance imaging
KW - Morphology
KW - Three-dimensional ultrasonography
KW - Ventriculomegaly
UR - http://www.scopus.com/inward/record.url?scp=80052325395&partnerID=8YFLogxK
U2 - 10.1007/s00404-010-1666-z
DO - 10.1007/s00404-010-1666-z
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C2 - 20830480
AN - SCOPUS:80052325395
SN - 0932-0067
VL - 284
SP - 331
EP - 336
JO - Archives of Gynecology and Obstetrics
JF - Archives of Gynecology and Obstetrics
IS - 2
ER -