Morphologic characterization off proliferative cells and virus particles in Turkeys with lymphoprolifferative disease

K. Perk, M. Ianconescu, A. Yaniv, A. Zlmber

Research output: Contribution to journalArticlepeer-review

Abstract

The tumors found In turkeys having lymphopro-llferative disease (LPD) are histologically characterized by a pleomorphic population of cells of the lymphoid series. Electron microscopy has shown that, despite marked differences In shape and size, the proliferating cells share basic ultrastructural features, Indicating their lymphoid origin. Virus particles morphologically and morphogenetlcally characteristic of type C oncornaviruses of Retravlrldae were found in different organs and plasma samples of diseased or Infected turkeys with LPD. This LPD type C virus resembled members of the retlculoendotheliosls virus group but not members of the avian sarcoma virus group.

Original languageEnglish
Pages (from-to)1483-1487
Number of pages5
JournalJournal of the National Cancer Institute
Volume62
Issue number6
DOIs
StatePublished - Jun 1979

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